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OBJECTIVE—To evaluate the within-trial effect of losartan and conventional antihypertensive therapy (CT) compared with placebo and CT on the economic cost
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A randomized trial comparing losartan with amlodipine as initial therapy for hypertension in the early post-transplant period (2006). Formica, Richard N.
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Key words: hypertension, losartan, valsartan, angiotensin II receptor blocker, active-control equivalence trial. (Clin Ther 2001;23:1166-1179) INTRODUCTION In
Atenolol vs. Losartan Clinical Trial Enrollment Sites. The following study sites are participating in the Atenolol vs. Losartan Clinical Trial and are also eligible to
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Please Search For Clinical Trials to view the most current clinical trials listings. Purpose: This study will explore the dose-response of losartan as well as the
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The main objective of this trial is to assess whether losartan treatment leads to a clinically relevant decrease of aortic dilatation in adult patients
Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomized trial-the Losartan Heart Failure Survival Study
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Effect of losartan on microalbuminuria in normotensive patients with type 2 diabetes mellitus: a randomized clinical trial.
Theoretically, both ACE inhibitors and losartan could adversely affect renal function in such sensitive patients. The ELITE trial showed a 10.5%
While the core trial is only studying the effect of losartan vs. atenolol on aortic aneurysm, efforts are under way to find funding for trials that can study losartan's
In the present case, the results of the trial depend on the interplay between the therapeutic intervention in the RENAAL study, i.e. losartan 50 or 100 mg daily,
Losartan Intervention For Endpoint Reduction in Hypertension Study. LIFE Study Overview. Double-blind, randomized trial to compare the effects of losartan and
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In this trial, losartan was efficacious and well tolerated, and was similar to placebo with regard to adverse-experience profile. Adverse experiences that could
Background— An echocardiographic substudy of the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial was designed to
Abstract and Introduction: Domenic Sica reviews the LIFE trial and gives expert commentary on results supporting the use of ARBs for
Addition of aliskiren to losartan in patients with hypertension and type 2 diabetes: AVOID trial. Source: N Engl J Med 2008; 358: 2433-2446,
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The Marfan Trial studies Beta Blocker Therapy (Atenolol) versus Angiotensin II Receptor Blocker Therapy (Losartan) in Individuals with Marfan
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Therapeutic Efficacy Three dose-ranging trials revealed that once-daily losartan 50 mg in combination with HCTZ 12.5 or 25 mg once daily (but
The losartan versus atenolol clinical trial has begun. The coordinators at each site are ready to receive calls and e-mails from anyone interested in participating.
A randomized trial comparing losartan with amlodipine as initial therapy for hypertension in the early post-transplant period. Authors: Formica
This assumed an annual mortality rate of 8.1% (candesartan group in the CHARM-Overall trial18) and 11.7% (losartan group in the ELITE II
Losartan Trial Investigators. Manolis AJ, Grossman E, Jelakovic B, Jacovides A, Bernhardi DC, Cabrera WJ, Watanabe LA, Barragan J, Matadamas N, Mendiola
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Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE). (PMID:9074572). Abstract
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Cardiovascular morbidity and mortality in the Losartan Intervention for Endpoint Reduction in hypertension study (LIFE): a randomized trial against atenolol.
Continuum of Renoprotection with Losartan at All Stages of Type 2 Diabetic Nephropathy: A Post Hoc Analysis of the RENAAL Trial Results
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Cardiovascular morbidity and mortality in the Losartan Intervention for Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol.
A comparative trial of controlled-onset, extended-release verapamil, enalapril, and losartan on blood pressure and heart rate changes. (PMID:11824861)
Description and results of Losartan Phase III International randomized clinical trial comparing Losartan, 50 mg daily vs Placebo in patients with heart failure who
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In clinical trials with losartan potassium-hydrochlorothiazide, no adverse experiences peculiar to this combination have been observed. Adverse experiences
In contrast to other more recent losartan trials (LIFE, RENAAL) [14,15], ELITE II used only a moderate dose of losartan: 50 mg daily. Consequently, HEAAL was
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Apart from their antihypertensive properties, some ARBs like losartan demonstrate anti platelet activity, as well as uricosuric properties. The trials of ARBs in
Data on health care resource utilization were collected as part of the trial. into a cost-effectiveness ratio of USD 4047 per year of life gained for losartan relative
Losartan Trial Investigators. AU. Manolis AJ, Grossman E, Jelakovic B, Jacovides A, Bernhardi DC, Cabrera WJ, Watanabe LA, Barragan J, Matadamas N,
Lay Summary, This is a randomized, controlled trial to determine whether Losartan is effective at slowing down, halting or reversing liver fibrosis in patients with
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Marfan syndrome (MFS) is one of the most common systemic disorders of connective tissue with the incidence of approximately 2-3 per 10 000 individuals.
Dickstein K, Kjekshus J. Comparison of the effects of losartan and captopril on mortality in patients after acute myocardial infarction: The OPTIMOL trial design.
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Paper 3759. 443. Introduction: The Losartan Intervention For. Endpoint reduction in hypertension (LIFE) study is the first, and, so far, the only endpoint trial in
Losartan Clinical trial. This ends the enrollment phase of the trial. The NMF would like to thank the Pediatric Heart Network, the trial sites, the patients and
Clinical Trials - clinicaltrials.gov Marfan syndrome is an inherited connective tissue disorder with morbidity and mortality from aortic dilation and dissectio
Effects of telmisartan, irbesartan, valsartan, candesartan, and losartan on cancers in 15 trials enrolling 138769 individuals. The ARB Trialists
Although the clinical trials will ultimately decide the safety and efficacy of losartan treatment for patients with Marfan syndrome, Dietz said the
Effects of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomized trial -- the Losartan Heart Failure Survival Study
Discussion: Domenic Sica reviews the LIFE trial and gives expert commentary on results supporting the use of ARBs for hypertension.
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The Losartan Intervention for Endpoint Reduction trial is one of several end-point trials that are now available with angiotensin-receptor blockers. This
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Diabetes Mellitus With the Angiotensin II Antagonist Losartan Trial, we determined the relationship between month 6 change in SUA and renal endpoints,
Telmisartan was superior to losartan on the primary endpoint, a change from of an extensive ongoing trial programme, including clinical and observational
Efficacy of Losartan in Preventing Progression of COPD | Clinical Research Trial Listing (COPD, Emphysema, Chronic Bronchitis, Smoking) (NCT00720226)
31 May 2011 Hoc Analysis of the Reduction of Endpoints in Non-Insulin-Dependent Diabetes Mellitus With the Angiotensin II Antagonist Losartan Trial
Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE). By - Dr
The story is our government didnt give permission for losartan trial.For this reason families and doctors began to try losartan themself.
Eighty percent of the total cohort completed the trial, 345 and 342 patients in the telmisartan and losartan groups, respectively. The mean
Mallion et al. recruited 223 patients with mild-to-moderate hypertension for a 6- week trial of telmisartan 40 mg or 80 mg and losartan 50 mg.1 Telmisartan 40 mg
Ruilope LM, Blood pressure, The purpose of this trial was to evaluate the antihypertensive efficacy of the concomitant administration of selected doses of
A randomized trial comparing losartan with amlodipine as initial therapy for hypertension in the early post-transplant period. Richard N. Formica Jr1,2, Amy L.
The OPTIMAAL trial: losartan or captopril after acute myocardial infarction. By - Kenneth Dickstein, John Kjekshus.
A randomized trial comparing losartan with amlodipine as initial therapy for hypertension in the early post-transplant period (2006). Formica Jr, Richard N.,
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The Marfan Trial Patients. This sheet (atenolol and losartan), to see which one is better at slowing the Losartan is a drug that is commonly used to treat high
The antihypertensive effects of losartan were demonstrated principally in 4 placebo-controlled, 6- to 12-week trials of dosages from 10 to 150 mg per day in
The antihypertensive effect of losartan was studied in one trial enrolling 177 hypertensive pediatric patients aged 6 to 16 years old. Children who weighed < 50
Effects of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial—the Losartan Heart Failure Survival Study
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losartan; angiotensin receptor blockers; hypertension; prognosis; clinical trial. It is no longer a question of 'should we treat' hypertension, but 'how to treat' and
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Losartan therapy in adults with Marfan syndrome: study protocol of the multi- center randomized controlled COMPARE trial. Teodora Radonic1*, Piet de Witte2 ,
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