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Abstract. Schulze-Neick I, Hartenstein P, Li J et al. Intravenous sildenafil is a potent pulmonary vasodilator in children with congenital heart disease. Circulation.
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Objective: To investigate the acute effects of intravenous sildenafil on haemodynamics and oxygenation, and its interaction with inhaled nitric oxide ( iNO) in
Eight infants received 20 ppm of iNO with the addition of intravenous Sildenafil ( 0.35 mg/kg over 20 min). Seven infants received intravenous
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Fraisse A. Intravenous sildenafil for postoperative pulmonary hypertension in children with congenital heart disease. CORD Conference
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Intravenous sildenafil is a potent pulmonary vasodilator in children with congenital heart disease. Circulation. 2003 Sep 9;108 Suppl 1:II167-73. PubMed PMID:
Schulze-Neick I, Hartenstein P, Li J, et al: Intravenous sildenafil is a potent pulmonary vasodilator in children with congenital heart disease.
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Anesthesiology Medical Article: Intravenous sildenafil for postoperative pulmonary hypertension in children with congenital heart disease.
investigated the acute effects of intravenous sildenafil on. 66 hemodynamics and oxygenation, and its interaction with. 67. iNO in infants at risk
The purpose of this study is to determine whether intravenous sildenafil reduces pulmonary artery pressure and improves oxygenation in
Among the subjects receiving sildenafil IV, the geometric mean Cmax and AUCt After IV administration, sildenafil Cmax occurred at the end of the 25-min
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Intravenous sildenafil lowers pulmonary vascular resistance in a model of neonatal pulmonary hypertension. Am J Respir Crit Care Med. 2002
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The Journal of Heart and Lung Transplantation, Volume 28, Issue 7, Pages 676- 682, July 2009, Authors:Phil Botha, MRCS; Gareth Parry, FRCP; John H. Dark,
Parker JD, Bart BA, Webb D, Koren MJ, Siegel R, Nicholas S, Wang H, Malhotra B. Safety of intravenous nitroglycerin after administration of sildenafil citrate to
PURPOSE: To evaluate the efficacy and safety of intravenous sildenafil for immediate postoperative pulmonary hypertension (PH) in pediatric
Generalized and cardiac sympathetic activity responses to an intravenous infusion of sildenafil were measured by the norepinephrine spillover
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Acute Hemodynamic Effects of Intravenous Sildenafil Citrate in Congestive Heart Failure: Comparison of Phosphodiesterase Type-3 and -5 Inhibition
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BACKGROUND: The reversibility of elevated pulmonary vascular resistance in heart failure bears an important relation to outcome after cardiac
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After observing the effect of intravenous sildenafil on neuropathic pain, RESULTS: Intravenous sildenafil dose-dependently increased the
We investigated the use of the phosphodiesterase-5 inhibitor sildenafil, in its intravenous form, as a pulmonary vasodilator in a model of meconium aspiration
One study evaluated the effects of a new intravenous sildenafil analogue--UK 343-664--compared with milrinone during acute pulmonary hypertension in a
The objective of the present study was to evaluate the effects of inhaled and intravenous sildenafil on the pulmonary endothelium-dependent relaxations, the
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Phil Botha, Gareth Parry, John H. Dark, Guy A. Macgowan. The Journal of Heart and Lung Transplantation, Vol. 28, No. 7. (July 2009), pp. 676-682.
Conclusions— Intravenous sildenafil is as effective as inhaled NO as a pulmonary vasodilator in children with congenital heart disease. Although clinically
Intravenous sildenafil lowers pulmonary vascular resistance in a model of neonatal pulmonary hypertension. Am J Resp Crit Care Med 2002
Intravenous Sildenafil in the Treatment of Neonates with Persistent Pulmonary Hypertension. Journal of Pediatrics, 2009-12-01, English, Article; Journal or
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Influence of intravenous sildenafil on cerebral oxygenation measured by near- infrared spectroscopy in infants after cardiac surgery. Nagdyman N, Fleck T,
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Effect of intravenous sildenafil on pulmonary hemodynamics and gas exchange in the presence and absence of acute lung injury in piglets.
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Sildenafil (Viagra) has been shown to be an effective pulmonary vasodilator and is increasingly used in patients with pulmonary hypertension.
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Intravenous sildenafil for postoperative pulmonary hypertension in children with congenital heart disease. [2011.03]. Sildenafil adjunctive therapy to risperidone
effectiveness of sildenafil in children with PHTN. While currently not available in the United States, intravenous sildenafil is associated with a significant
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NeLM news service. EC approves intravenous sildenafil (Revatio®) for pulmonary arterial hypertension. Source: BioSpace. Date published: 05/01/2010 15:36
intravenous sildenafil bolus in pulmonary arterial hypertension (PAH) patients stabilized Although further research is warranted, a 10 mg sildenafil intravenous
Dose response of intravenous sildenafil on systemic and regional hemodynamics in hypoxic neonatal piglets. Haase E, Bigam DL, Cravetchi O, Cheung PY.
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Pediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development,
Intravenous sildenafil is a potent pulmonary vasodilator in children with congenital heart disease. Schulze-Neick, I. and Hartenstein, P. and Li,
To assess pharmacokinetics and pharmacodynamics of a 10-mg intravenous sildenafil bolus in pulmonary arterial hypertension (PAH) patients
In neonates with acute pulmonary hypertension (PHT), the dose-response effect of sildenafil citrate,
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Intravenous sildenafil lowers pulmonary vascular resistance in a model of neonatal pulmonary hypertension. Am J Respir Crit Care Med 2002
Viagra (sildenafil) can be used safely in most patients with heart disease PURPOSE: To evaluate the efficacy and safety of intravenous sildenafil for immediate
Oral sildenafil was instituted at a dose of 2 mg/kg every 6 hours following a poor response to intravenous prostacyclin. Serial measurement of oxygen saturation
The use of sildenafil in children has been described only in case reports6-9 and in one randomized study that compared the use of iNO and intravenous
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Effect of intravenous sildenafil on right and left ventricular function in pigs. Please use this identifier to cite or link to this item:
After observing the effect of intravenous sildenafil on
Intravenous sildenafil as a preconditioning drug against hemodynamic consequences of warm ischemia-reperfusion on the kidney.
Sildenafil injection is used to treat the symptoms of pulmonary arterial hypertension. This is a type of high blood pressure that occurs between
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Safety, tolerability and pharmacokinetics of an intravenous bolus of sildenafil in patients with pulmonary arterial hypertension. Jean-Luc
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Intravenous sildenafil lowers pulmonary vascular resistance in a model of neonatal pulmonary hypertension. Am J Respir Crit Care Med. 2002;165: 1098- 102.
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sildenafil compared with inhaled nitric oxide (NO) and intravenous maximum tolerated doses of intravenous SNP and sildenafil, (5 gkg 1 min 1 and 0.1 mgkg 1
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of intravenous sildenafil to animals that were already receiving iNO augmented the cGMP-dependent pulmon- ary vasodilation and resulted in systemic
Correction: Addition of Sildenafil to Long-Term Intravenous Epoprostenol Therapy in Patients with Pulmonary Arterial Hypertension
effects of a combination of iNO and intravenous sildenafil in post-operative patients and found that though both drugs reduced the pulmonary resistance
Combination Therapy of Brain Natriuretic Peptide and Sildenafil Attenuates (n= 5), intravenous Sildenafil (84 mg/kg/min; n=8), and intravenous BNP (100
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Studies assessing the effects of intravenous sildenafil showed that phosphodiesterase-5 inhibition potentiated response to iNO during cardiac catheterization
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