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In IDEAL, high-dose atorvastatin (80 mg/day) was associated with increased transaminase elevations (0.97% vs 0.11%, p < 0.001), myalgias (2.2% vs 1.1%,
Atorvastatin 80 mg, Control, HR (95% CI), P. SPARCL, 8.71, 6.06, 1.37 (1.08-1.75 ), 0.011. TNT, 9.24, 8.11, 1.10 (0.94-1.29), 0.226. IDEAL, 6.40
In the IDEAL study, atorvastatin 80 mg daily effectively and safely reduced the primary endpoint of major coronary events in patients with a history of myocardial
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In the peripheral step-down in Endpoints through aggressive lipoid lowering study (IDEAL), treatment with Lipitor 80 mgday was compared to treatment with
Intensive lipid lowering with atorvastatin 80 mg did not result in a significant reduction in the primary end point of major coronary events when
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Cost-effectiveness of high-dose atorvastatin compared with usual-dose simvastatin: less than IDEAL? This editorial refers to 'Cost-effectiveness
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In the IDEAL (Incremental Decrease in End Points Through Aggressive Lipid Lowering) trial, 239 of 3737 patients randomized to atorvastatin 80 mg/day and 208
Over global IDEALS the sample ideal was an open label attempt of 8. 888 patients, who had had a preceding cardiac infarct compare Lipitor 80
The Incremental Decrease in End Points Through Aggressive Lipid Lowering ( IDEAL) study compared atorvastatin 80mg daily with simvastatin 20mg daily
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Thus patients in IDEAL were randomly assigned to receive a high dose of atorvastatin (80 mg/d; n = 4439), or usual-dose simvastatin (20 mg/d; n = 4449).
Atorvastatin 80. 77. 0.72 (0.52,0.98). A to Z (4497). Simvastatin 80. 63. 0.54 (0.34, 0.85). PROVE-IT (4162). Atorvastatin 80. 62. 0.80 (0.61,1.05). IDEAL (8888)
The current analysis focuses on atorvastatin's effects in the TNT, IDEAL, and SPARCL trials. It found that atorvastatin, when compared with
About the Overall IDEAL Trial IDEAL was an open-label trial of 8888 patients who had had a previous heart attack comparing Lipitor 80 mg with simvastatin 20
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Cost-effectiveness of high-dose atorvastatin compared with usual-dose simvastatin: less than IDEAL? Padma Kaul. Department of Medicine
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